What is The Sinclair Method (TSM)?
A treatment for alcohol addiction that uses a technique called pharmacological extinction—the use of an opiate blocker to turn habit-forming behaviors into habit-erasing behaviors. The effect returns a person's craving for alcohol to its pre-addiction state.
TSM consists of taking Naltrexone or Nalmefene one hour before your first drink of the day for the rest of your life as long as you continue to drink. Naltrexone (or Nalmefene) chemically disrupts the body’s behavior/reward cycle causing you to want to drink less instead of more.